12/7/2023 0 Comments Vaccine side effect tracker![]() ![]() In 2019, the World Health Organization set out hesitancy regarding immunizations and the associated risks to society’s health in the list of the ten biggest threats to human health worldwide. While in some parts of the world (mainly in sub-Saharan Africa) inequalities in access to vaccines have emerged as a major problem, in others, vaccine hesitancy is a major barrier to controlling the spread of the virus. At the end of week 48 in 2021, the 14-day COVID-19 death rate in Bulgaria was 233.8 per million population (for the EU / EEA was 55.9 deaths). The 14-day notification rate of COVID-19 deaths reflects this low use of vaccination, with deaths in our country many times higher than the average for the EU/EEA. This indicator is two and a half times lower than the one registered in the EU / EEA–the cumulative uptake of full vaccination among adults (18+) is 78.6% (according to ECDC COVID-19 Vaccine Tracker). According to the COVID-19 Unified Information Portal, as of December 13, 2021, a total of 3 494 341 doses of vaccines against COVID-19 have been delivered in Bulgaria, or 31.8% of the population (over 18 years) have completed a vaccination course. Īmong the countries in the European Union (EU) / European Economic Area (EEA), where vaccines against COVID-19 are available and affordable, Bulgaria reports the lowest immunization coverage and the most pronounced vaccine distrust. On the other hand, many unresolved issues, such as the duration of post-vaccination protection, the need for additional doses, the emergence and circulation of new variants, and the fear of potential short- or long-term side effects are some of the reasons for COVID-19 vaccine hesitancy. Immunization strategies with available vaccines against COVID-19 provide the greatest hope and most effective way to achieve herd protection. Both pharmaceutical and non-pharmaceutical countermeasures have been used to deal with this global threat. The emergence of a new, pandemic pathogen-SARS-CoV-2- at the end of 2019 put humanity in need of urgent action through the worldwide integration of intellectual and financial resources. Historically, vaccines have been widely recognized as a key tool for the successful prevention and control of communicable diseases. The reported reactions are relatively high but expected and no adverse events have been reported that are not listed in the official Summary of Product Characteristics. There were 3 reports of generalized urticaria after an mRNA and 2 after an adenoviral vector vaccine. None of the registered systemic reactions required medical attention. An association was found between the systemic reactions and the type of vaccine administered: 59.7% in mRNA recipients and 89.4% in adenoviral vector vaccinees (p<0.001). The most common types of systemic reactions were fatigue, headache, and muscle pains. The levels of local reactions were comparable: 91.7% in those who received mRNA and 89.7% in those who received an adenoviral vector vaccine (p = 0.366). They were mild to moderate and resolved within several days. Statistical significance was set at p0.05). ![]() ![]() Descriptive statistics parametric and non-parametric methods were applied. A cross-sectional survey-based study, covering 761 vaccinated respondents, was conducted in Plovdiv (469 with an mRNA vaccine and 292 with an adenoviral vector vaccine). The present study aimed to assess the self-reported adverse reactions following COVID-19 vaccination as a possible tool to increase the trust in vaccines. As a member state of the European Union, where vaccines against COVID-19 are available and affordable, Bulgaria reports the lowest immunization coverage and the most pronounced vaccine distrust.
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